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Guide — graded by evidence

Peptides for sleep & circadian, graded by evidence

Compounds studied for sleep & circadian, ranked by the strength of the evidence — strongest at the top, research-grade and disappointing below. Grades reflect the evidence, not marketing. This is a neutral reference; nothing here is a recommendation to use, and no compound is offered for sale.

B
MK-677 (Ibutamoren)Small molecule (non-peptide)

MK-677 (ibutamoren) is an oral, non-peptide ghrelin-receptor agonist — the pill version of the injectable GHRPs.

#1
C

DSIP (regulatory name Emideltide) is a naturally occurring nonapeptide named for its ability to promote delta (deep-sleep) EEG in rabbits.

#2
C

Epitalon is a synthetic tetrapeptide (AEDG) from Russian pineal-peptide research, heavily promoted for telomerase activation and longevity.

#3

Ranking is by evidence grade (A–F), the same ceiling shown on each compound page — not by popularity or margin. No dosing, reconstitution, or administration is given anywhere on Vallydia. See each entry for its full evidence table and legal status by region.

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Region — United States
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This site provides neutral scientific reference and sells only products lawful in your region. Nothing here is medical advice, a recommendation, or an offer to supply unapproved medicines. No dosing or administration is published for research compounds. Cosmetic peptides per Regulation (EC) 1223/2009. Unapproved injectable peptides are neither sold nor advertised in the EU (Directive 2001/83/EC, Title VIII). © 2026 Vallydia SL — Registered in Spain.

Peptides for sleep & circadian, graded by evidence · Vallydia