Compounds studied for hair & topical, ranked by the strength of the evidence — strongest at the top, research-grade and disappointing below. Grades reflect the evidence, not marketing. This is a neutral reference; nothing here is a recommendation to use, and no compound is offered for sale.
GHK-Cu is a naturally occurring copper-binding tripeptide.
A wool-derived protein hydrolysate used across hair care, and one of the better evidenced conditioning actives on the shelf, with a catch that undermines the ingredient list…
The ethanolamine salt of piroctone, and the active that now anchors most European anti-dandruff shampoos.
A zinc compound used against dandruff for more than sixty years, and the register's sharpest illustration that safe and lawful are different questions.
AHK-Cu is a copper-binding tripeptide engineered for hair (whereas GHK-Cu targets skin).
The molecule that created the bond-building category, sold on the proposition that it travels into the hair cortex and reconstructs the disulfide bridges that bleach destroys.
An azole antifungal used in anti-dandruff shampoos, and one of the actives that absorbed the European market after zinc pyrithione was prohibited in 2022.
Hydrolyzed wheat protein is a surface film-former that makes skin and hair feel smoother and look glossier — a real but superficial cosmetic effect, graded C.
A steam-distilled essential oil that became the most confidently repeated claim in hair care on the strength of a single trial.
PTD-DBM is a synthetic peptide designed to switch on Wnt/β-catenin signalling — a core hair-follicle growth pathway — by blocking CXXC5, a protein that normally puts the brakes…
Ranking is by evidence grade (A–F), the same ceiling shown on each compound page — not by popularity or margin. No dosing, reconstitution, or administration is given anywhere on Vallydia. See each entry for its full evidence table and legal status by region.
A neutral reference and a lawful-lane shop. Information for those who seek it — never promotion.
This site provides neutral scientific reference and sells only products lawful in your region. Nothing here is medical advice, a recommendation, or an offer to supply unapproved medicines. No dosing or administration is published for research compounds. Cosmetic peptides per Regulation (EC) 1223/2009. Unapproved injectable peptides are neither sold nor advertised in the EU (Directive 2001/83/EC, Title VIII). © 2026 Vallydia.