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Explore  /  Guides  /  Anti-inflammatory
Guide — graded by evidence

Peptides for anti-inflammatory, graded by evidence

Compounds studied for anti-inflammatory, ranked by the strength of the evidence — strongest at the top, research-grade and disappointing below. Grades reflect the evidence, not marketing. This is a neutral reference; nothing here is a recommendation to use, and no compound is offered for sale.

A

LL-37 is the body's own broad-spectrum antimicrobial peptide — the only human cathelicidin — a 37-amino-acid innate-immune effector made by skin and immune cells, switched on by…

#1
A
OxytocinPeptide

Oxytocin is a 9-amino-acid endogenous hormone with two lives.

#2
A

VIP is a 28-amino-acid endogenous neuropeptide with broad, well-established physiology — it's a potent vasodilator and bronchodilator, a strong anti-inflammatory/immune…

#3
B

Dasatinib+Quercetin (D+Q) and Fisetin are the first and best-known senolytics — drugs that selectively kill senescent "zombie" cells, which accumulate with age and pump out an…

#4
C
KPVPeptide

KPV is the anti-inflammatory C-terminal tripeptide of α-MSH — the same hormone behind the melanotan and PT-141 peptides, but stripped of all melanocortin-receptor activity (no…

#5
C

TB-500 is a synthetic actin-binding fragment related to Thymosin Beta-4, studied mainly in animal models for tissue repair, wound healing and inflammation.

#6
D

ARA-290 (cibinetide) is an 11-amino-acid peptide copied from the helix-B surface of erythropoietin.

#7
D
MangiferinSmall molecule (non-peptide)

Mangiferin is a xanthonoid polyphenol from mango with a strong in-vitro antioxidant and anti-inflammatory profile, which is why it appears in some antioxidant cosmetic…

#8
D
QuercetinSmall molecule (non-peptide)

Quercetin is one of the most abundant and most-studied plant flavonols — a potent in-vitro antioxidant and anti-inflammatory found in onions, apples and many plants.

#9
F
ApelinPeptide

Apelin is an endogenous peptide and the natural ligand of the APJ receptor, a G-protein-coupled receptor closely related to the angiotensin II receptor.

#10
F
B7-33Peptide

B7-33 is a designed single-chain peptide derived from the B-chain of H2 relaxin, built to keep relaxin's anti-fibrotic activity while shedding the difficulties of the full…

#11

Ranking is by evidence grade (A–F), the same ceiling shown on each compound page — not by popularity or margin. No dosing, reconstitution, or administration is given anywhere on Vallydia. See each entry for its full evidence table and legal status by region.

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This site provides neutral scientific reference and sells only products lawful in your region. Nothing here is medical advice, a recommendation, or an offer to supply unapproved medicines. No dosing or administration is published for research compounds. Cosmetic peptides per Regulation (EC) 1223/2009. Unapproved injectable peptides are neither sold nor advertised in the EU (Directive 2001/83/EC, Title VIII). © 2026 Vallydia.