Compounds studied for gh & endocrine, ranked by the strength of the evidence — strongest at the top, research-grade and disappointing below. Grades reflect the evidence, not marketing. This is a neutral reference; nothing here is a recommendation to use, and no compound is offered for sale.
Tesamorelin is a stabilized 44-amino-acid GHRH analog and the only GHRH analog with a current FDA approval (as Egrifta, for HIV-associated lipodystrophy since 2010).
Bimagrumab is a monoclonal antibody that blocks the activin type II receptors, producing a unique effect — fat loss with simultaneous muscle gain.
CJC-1295 is a long-acting synthetic GHRH analog that reliably raises GH and IGF-1 in humans (shown in a Phase 1 trial).
GHRP-2 (pralmorelin) is a ghrelin-receptor agonist and the only GHRP with a regulatory approval — in Japan, as a diagnostic agent for GH deficiency.
GHRP-6 is the original growth-hormone-releasing peptide (Bowers, 1984) — the compound from which the entire GH-secretagogue class descends, and whose study led to the discovery…
Hexarelin (examorelin) is the most potent classic GHRP and the most distinctive — uniquely, alongside the ghrelin receptor it binds the cardiac CD36 receptor, producing direct…
Ipamorelin is a selective ghrelin-receptor agonist that raises GH in a clean pulse (without the cortisol/prolactin rise of older GHRPs) — a real and well-characterised…
MK-677 (ibutamoren) is an oral, non-peptide ghrelin-receptor agonist — the pill version of the injectable GHRPs.
Sermorelin is GHRH(1-29), the shortest fully active fragment of GHRH, and the only GH secretagogue with a genuine FDA-approval history (as Geref, for pediatric GH deficiency and…
Gonadorelin is the synthetic form of GnRH, the natural hypothalamic decapeptide that tells the pituitary to release LH and FSH — the master switch of the reproductive hormone axis.
MGF (Mechano Growth Factor, IGF-1Ec) is a splice variant of IGF-1 produced locally in muscle in response to mechanical stress or damage.
IGF-1 LR3 is a long-acting engineered version of IGF-1, prized in the muscle community for one genuinely special property — hyperplasia, the formation of new muscle fibres via…
Ranking is by evidence grade (A–F), the same ceiling shown on each compound page — not by popularity or margin. No dosing, reconstitution, or administration is given anywhere on Vallydia. See each entry for its full evidence table and legal status by region.
A neutral reference and a lawful-lane shop. Information for those who seek it — never promotion.
This site provides neutral scientific reference and sells only products lawful in your region. Nothing here is medical advice, a recommendation, or an offer to supply unapproved medicines. No dosing or administration is published for research compounds. Cosmetic peptides per Regulation (EC) 1223/2009. Unapproved injectable peptides are neither sold nor advertised in the EU (Directive 2001/83/EC, Title VIII). © 2026 Vallydia.